Sodium selenate

ثبت نشده
چکیده

Human toxicity Elemental selenium metal has a relatively low order of toxicity. Acute poisoning with selenium and its salts are rare, however, in excessive amount toxic and even fatal action was documented. Normal whole blood selenium levels in adults range from 0.085 to 0.13 mg/l [2]. All selenium salts can produce toxicity by ingestion, inhalation, and percutaneous absorption, although specific information on the possible dermal absorption of sodium selenate was not found. Sodium selenate is the least toxic inorganic selenium form; sodium selenite (Na2SeO3) is more toxic [3]. Several toxic symptoms are listed here [1]: cardiovascular: ECG changes indicating myocardial damage; hypotension; in severe cases – fatal cardiac arrest; respiratory: pulmonary edema, respiratory tract irritation, cough, and respiratory failure; neurologic: CNS depression, convulsions (at acute selenium poisoning), dizziness, irritability, restlessness, headache, and coma; gastrointestinal: nausea, vomiting, salivation, and gastrointestinal pain.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

اثر متقابل متیل جاسمونات و سلنات سدیم بر برخی پارامترهای فیزیولوژیکی درگیاه گوجه فرنگی (Lycopersicon esculentum Mill.)

Selenium is an essential element in some organisms, but high concentrations can leading to toxicity in plant. Methyl jasmonate hormone plays an important role in defence processes. In this research, the effect of Methyl jasmonate (Me JA) and sodium selenate (Na2SeO4 ) on growth, content of pigments, phenol, anthocyanin and proline in tomato plants were studied. The seeds to germinate in petri...

متن کامل

Selenite and selenate inhibit human lymphocyte growth via different mechanisms.

Selenium compounds like selenite and selenate have strong inhibitory effects, particularly on mammalian tumor cell growth by unknown mechanisms. We found that the addition of sodium selenite and sodium selenate inhibited the growth of human 3B6 and BL41 lymphocytes. Selenite was more potent because 10 microM selenite produced a growth inhibitory effect similar to that of 250 microM selenate. Th...

متن کامل

Impact of selenite and selenate on differentially expressed genes in rat liver examined by microarray analysis.

Sodium selenite and sodium selenate are approved inorganic Se (selenium) compounds in human and animal nutrition serving as precursors for selenoprotein synthesis. In recent years, numerous additional biological effects over and above their functions in selenoproteins have been reported. For greater insight into these effects, our present study examined the influence of selenite and selenate on...

متن کامل

Comparative oral dose toxicokinetics of selenium compounds commonly found in selenium accumulator plants.

Consumption of Se accumulator plants by livestock can result in Se intoxication. Recent research indicates that the Se forms most common in Se accumulator plants are selenate and Se-methylselenocysteine (MeSeCys). In this study the absorption, distribution, and elimination kinetics of Se in serum and whole blood of lambs dosed with a single oral dose of (1, 2, 3, or 4 mg Se/kg BW) of sodium sel...

متن کامل

Changes in SeMSC, glucosinolates and sulforaphane levels, and in proteome profile in broccoli (Brassica oleracea var. Italica) fertilized with sodium selenate.

The aim of this work was to analyze the effect of sodium selenate fortification on the content of selenomethyl selenocysteine (SeMSC), total glucosinolates and sulforaphane, as well as the changes in protein profile of the inflorescences of broccoli (Brassica oleracea var. Italica). Two experimental groups were considered: plants treated with 100 μmol/L sodium selenate (final concentration in t...

متن کامل

Biliary excretion of selenium in the dog after administration of sodium selenate containing radioselenium.

Selenium is known to be present in the bile of selenium-treated animais. Smith et al. (I) reported that rabbit bile, after acute and subacute poisoning with sodium selenite and selenate (0.5 to 3 mg. of selenium per kilo), contained smaller amounts of selenium (36 to 48 y per cent) after oral treatment than after intravenous treatment (336 y per cent). In studies by Dudley (2), it was found, af...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013